SDMA testing data supports that kidney disease is over 2 times more common than previously reported. It also clearly shows SDMA is increased more frequently as pets progress in age, providing solid evidence that as dogs and cats age, they are more likely to develop chronic kidney disease. 1 Review SDMA results, including our current understanding of results when SDMA is increased and creatinine is normal as well as at the rare results when creatinine is increased and SDMA is normal.